Birth Defects News
June 29, 2023

Top Headlines

Human Embryo-Like Models Created from Stem Cells to Understand Earliest Stages of Human Development

Scientists have created a stem cell-derived model of the human embryo in the lab by reprogramming human stem cells. The breakthrough could help research into genetic disorders and in understanding why and how pregnancies ...

What Role Does Alternative Splicing Play in Neurodegenerative Disease?

Scientists have written a review to discuss emerging research and evidence of the roles of alternative splicing defects in major neurodegenerative diseases. They also summarize the latest advances in RNA-based therapeutic strategies to target these ...

Open-Analysis Platform for Pediatric Brain Tumors Provides Robust Data Resource for Childhood Cancer Research

研究人员合作创建一个first-of-its-kind open-source, reproducible analysis platform for pediatric brain tumors. With the help of thousands of genomically sequenced samples, researchers have used this platform to identify initial ...

Scientists Unveil RNA-Guided Mechanisms Driving Cell Fate

The early stages of embryonic development contain many of life's mysteries. Unlocking these mysteries can help us better understand early development and birth defects, and help develop new regenerative medicine treatments. Researchers have now characterized a critical time in mammalian embryonic ...

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Understanding the Speed of Brain Communication

Called the human connectome, this structural system of neural pathways develops as people age. A new study shows transmission speed among brain regions increases into early adulthood. Learning more ...

一个微型的心我n a Petri Dish: Organoid Emulates Development of the Human Heart

A team has induced stem cells to emulate the development of the human heart. The result is a sort of 'mini-heart' known as an organoid. It will permit the study of the earliest development ...

Living With Pet Cats or Dogs Is Associated With Fewer Food Allergies in Young Children, Study Finds

In an analysis of over 65,000 infants from Japan, children exposed to pet cats or indoor dogs during fetal development or early infancy tended to have fewer food allergies compared to other ...

Lone Star Tick Bites May Be to Blame for Unexplained Digestive Problems

New clinical guidance has been developed to help physicians and patients identify if unexplained digestive symptoms are due to alpha-gal syndrome, a food allergy that is caused by lone star tick ...

Children at Risk of Multiple Sclerosis Often Go Undetected in Early Stages

Criteria used by neurologists to assess for multiple sclerosis (MS) in adults may fail to identify the illness in children with imaging suspicious for the disease, an oversight that could delay ...

Solving the Alzheimer's Disease Puzzle: One Piece at a Time

Researchers have uncovered a novel regulatory mechanism in the brain that is essential for making the right kinds of proteins that promote healthy brain function, and its malfunctioning may be an ...

Molecular Mechanism of Hydrocephalus Could Lead to the First-Ever Non-Surgical Treatment

Researchers have learned that the same molecular pathway is involved in both the infectious and hemorrhagic forms of acquired hydrocephalus, a life-threatening disease that triggers a massive ...

Study Reveals Limitations in Evaluating Gene Editing Technology in Human Embryos

A commonly used scientific method to analyze a tiny amount of DNA in early human embryos fails to accurately reflect gene edits, according to new research. Although gene editing technologies hold ...

Assessing the Risk of Excess Folic Acid Intake

Researchers assessed in an animal model the effect of folic acid supplementation on mutation rates and other genetic ...

Pregnant Patients With Anxiety Have Altered Immune Systems

The immune system of pregnant women with anxiety is biologically different from that of pregnant women without anxiety, according to new ...

New Link Between Fatal Muscle Wasting Disease Gene and Cancer Discovered

New research has uncovered a novel link between the Duchenne muscular dystrophy (DMD) gene and ...


The Far-Reaching Consequences of Child Abuse

Adverse childhood experiences in mothers can affect their children's mental and physical health, as researchers report. The study found that maltreatment during a mother's childhood is ...

What Makes the Immune Systems of Prematurely Born Babies Susceptible to Deadly Infections?

Physicians have discovered why the immune system of prematurely born babies is not working optimally after ...

New Insights Into Fetal Development May Protect Against Leukaemia

During the fetal stage, a number of so-called cell programs run that are vital to the development of the fetus. Researchers demonstrate that one of these fetal programs appears to protect against ...

Fragile X Syndrome: Sensory Signals from Outside World Are Underrepresented by Cortical Pyramida, Study Shows

In Fragile X syndrome, sensory signals from the outside world are integrated differently, causing them to be underrepresented by cortical pyramidal neurons in the brain, according to a new ...

Mothers' Alcohol Consumption Before and During Pregnancy Is Linked to Changes in Children's Face Shapes

Researchers have used artificial intelligence to discover a link between alterations in the shape of children's faces and the amount of alcohol their mothers drank, before and during pregnancy. ...

New Study Identifies Risk Factors Associated With Low Birthweights

Multiple births, a short interval between pregnancies and mothers with a maternal physical or mental health condition are more at risk of having a low birth rate baby. Every year 20 million children ...

Drug Alleviates Autism-Associated Behavior in Mice

The behavioral disorders observed in autism are associated with a multitude of genetic alterations. Scientists have now found another molecular cause for this condition. The transcription factor ...

Disrupted Flow of Brain Fluid May Underlie Neurodevelopmental Disorders

Researchers have discovered, in rodents, that fluid that circulates through the brain flows to areas critical for normal brain development and function, suggesting that disruptions to its circulation ...

Brain Injuries Drop 20% for Babies With Heart Defects

Recent advances in newborn heart surgery have greatly reduced brain injuries in infants with congenital heart disease, according to a 20-year ...

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