Pharmaceuticals News
June 29, 2023

Top Headlines

New Drug Delivery Method Can Reverse Senescence of Stem Cells

随着年龄的增长,我们的身体变化和退化/ time in a process called senescence. Stem cells, which have the unique ability to change into other cell types, also experience senescence, which presents an issue when trying to maintain cell cultures for therapeutic use. The biomolecules produced ...

Drug Decelerates Bacterial Race to Antibiotic Resistance

Researchers report that, in laboratory cultures and animal models, a drug significantly reduces the ability of bacteria to develop antibiotic resistance, which might prolong antibiotic ...

Repurposed Drug Shows Promise for Treating Cardiac Arrhythmias

Researchers invented a new reporting technique to monitor activity of CaMKII while screening the effects of nearly 5,000 FDA approved drugs on human cells that expressed the enzyme. The screen identified five previously unknown CaMKII inhibitors; ruxolitinib, which is used to treat cancers of the ...

Can This Medication Reverse MS? Brain Biomarker Shows It Can

A decade after scientists identified an over-the-counter antihistamine as a treatment for multiple sclerosis, researchers have developed an approach to measure the drug's effectiveness in repairing the brain, making it possible to also assess future therapies for the devastating ...

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Earlier Headlines

Cellular Traffic Controllers Caught Managing Flow of Signals from Receptors

Proteins that act like air traffic controllers, managing the flow of signals in and out of human cells, have been observed for the first time with unprecedented detail using advanced microscopy ...

New Test Reveals Existing Antibiotics, Hiding in Plain Sight on Pharmacy Shelves, Can Treat Superbugs

A new test revealed that FDA-approved antibiotics -- available at your neighborhood pharmacy -- can effectively treat superbugs. They are not prescribed, however, because the gold-standard test ...

First 'Gene Silencing' Drug for Alzheimer's Disease Shows Promise

A new trial has found a new genetic therapy for Alzheimer's disease that is able to safely and successfully lower levels of the harmful tau protein known to cause the ...

New Biologic Effective Against Major Infection in Early Tests

一个研究小组通过初步检测bioengineered drug candidate can counter infection with Staphylococcus aureus -- a bacterial species widely resistant to ...

Drug Combination Restores Ability of Leading Treatment to Signal for Death of Blood Cancer Cells

Despite the promise of new medications that promote cancer cell death in people with acute myeloid leukemia, leukemic cells often adopt features that let them evade the drugs' effects within a ...

Nanoparticles Provoke Immune Response Against Tumors but Avoid Side Effects

Researchers find that when immunostimulatory drugs called imidazoquinolines are delivered using specialized bottlebrush nanoparticles, the drugs provoke the immune system to attack tumors while ...

Wonder Drug-Capsule May One Day Replace Insulin Injection for Diabetics

Scientists have designed a new type of oral capsule that could mean pain-free delivery of insulin and other protein drugs. Protein drugs had proven challenging to deliver orally as the drugs degrade ...

Molecular 'Superpower' of Antibiotic-Resistant Bacteria

A species of ordinary gut bacteria that we all carry flourishes when the intestinal flora is knocked out by a course of antibiotics. Since the bacteria is naturally resistant to many antibiotics, it ...

How Drugs Get Into the Blood

Computer simulations have helped researchers understand in detail how pharmaceutically active substances cross cell membranes. These findings can now be used to discover new drug candidates more ...

Implantable Device Shrinks Pancreatic Tumors

Nanomedicine researchers have found a way to tame pancreatic cancer -- one of the most aggressive and difficult to treat cancers -- by delivering immunotherapy directly into the tumor with a device ...

Novel Immunotherapy Agent Safe, Shows Promise Against High-Risk Prostate Cancers

A new drug, a monoclonal antibody known as enoblituzumab, is safe in men with aggressive prostate cancer and may induce clinical activity against cancer throughout the body, according to a phase 2 ...


Super-Sized Nanocage Could Deliver Bigger Drug Cargoes

Nanocages are tiny artificial containers that can be used to deliver therapeutics to a target destination in the body. But some drug molecules are like gifts that are too big for a standard-sized ...

Fight Against Treatment-Resistant Superbugs

研究人员正在研究的超级细菌的基因aid the development of new and effective treatments for drug-resistant bacterial infections. Superbugs are characterized as infection-causing ...

Novel Drug Offers Hope for Heart Failure Patients

A novel drug is showing promise for alleviating both heart failure and the sleep apnea associated with ...

Marijuana-Derived Compounds Could Reverse Opioid Overdoses, Researchers Report

Naloxone -- a fast-acting opioid antidote -- has saved lives, but it's less effective against powerful synthetic opioids, such as fentanyl. In an interesting twist, researchers are now ...

Fibroblast Inhibitors Assist Anti-Cancer Drugs to Suppress Cancer Growth

Researchers develop a 3D cell culture system to test how inhibiting fibroblast activities can help treat lung cancer. To simulate the tumor microenvironment and mimic real tissues, the team ...

Known Active Ingredient as New Drug Candidate Against Mpox

Mpox -- previously known as 'monkeypox' -- is currently spreading worldwide. Researchers have now identified a compound that could help fight the ...

Novel Drug Makes Mice Skinny Even on Sugary, Fatty Diet

Deleting a gene that promotes magnesium transport into mitochondria (which are cells' power plants) resulted in more efficient metabolism of sugar and fat in the energy centers. The result: ...

Emergence of Extensively Drug-Resistant Shigella Sonnei Strain in France

Shigellosis, a highly contagious diarrheal disease, is caused by Shigella bacteria circulating in industrializing countries but also in industrialized countries. Scientists who have been monitoring ...

Can Lymph Nodes Boost the Success of Cancer Immunotherapy?

Cancer treatment routinely involves taking out lymph nodes near the tumor in case they contain metastatic cancer cells. But new findings from a clinical trial show that immunotherapy can activate ...

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