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Pharmacology News
June 29, 2023

Top Headlines

An Unexpected Doorway Into the Ear Opens New Possibilities for Hearing Restoration

Researchers have developed a new method to deliver drugs into the inner ear. The discovery was possible by harnessing the natural flow of fluids in the brain and employing a little understood backdoor into the cochlea. When combined to deliver a ...

Researchers Show How a Tumor Cell's Location and Environment Affect Its Identity

Using 3-D models of ovarian cancer tumors, scientists found differences in gene activity based on where a cell is in a tumor, demonstrating how a cell's location and environment in a cancerous tumor can strongly influence which genes are active and ...

New Drug Delivery Method Can Reverse Senescence of Stem Cells

As we age, our bodies change and degenerate over time in a process called senescence. Stem cells, which have the unique ability to change into other cell types, also experience senescence, which presents an issue when trying to maintain cell cultures for therapeutic use. The biomolecules produced ...

Novel Study Deepens Knowledge of Treatment-Resistant Hypertension

Novel research found that apparent resistant hypertension (aRH) prevalence was lower in a real-world sample than previously reported, but still relatively frequent -- affecting nearly 1 in 10 hypertensive ...
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New Diagnostic Finds Intact Sperm in Infertile Men

Researchers develop new diagnostic tool to visualize protein biomarkers of well-developed sperm to determine if surgical sperm extraction may be successful for certain infertile ...

Biodegradable Ultrasound Opens the Blood-Brain Barrier

A new, biodegradable ultrasound far more powerful than previous devices could make brain cancers more treatable, researchers ...

米icroplastics Stick Around in Human Airways

Inhaled microplastics can pose serious health risks, so understanding how they travel in the respiratory system is essential for prevention and treatment of respiratory diseases. Researchers develop ...

Serotonin Booster Leads to Increased Functional Brain Connectivity

Cognitive deficits accompany mood disorders and other psychiatric conditions, often with debilitating effects. Limited treatments currently exist, but studies in animals and humans have pointed to ...

这药物逆转女士吗?大脑的生物标志物Shows It Can

A decade after scientists identified an over-the-counter antihistamine as a treatment for multiple sclerosis, researchers have developed an approach to measure the drug's effectiveness in ...

阻止免疫系统的“信使”可能治疗切断e Asthma

Asthma is more dangerous than many people realize. An estimated 10 Americans die every day from asthma, and the disease leads to around 439,000 hospitalizations and 1.3 million emergency room trips ...

Breakthrough in Glioblastoma Treatment With the Help of a Virus

Researchers are describing the results of a recent clinical trial -- a breakthrough in glioblastoma treatment with the help of a modified cold virus injected directly into the tumor. When combined ...

New Model Offers a Way to Speed Up Drug Discovery

A model known as ConPLex can predict whether potential drug molecules will interact with specific protein targets, without having to perform the computationally intensive calculation of the ...

A New Way to Develop Drugs Without Side Effects

Have you ever wondered how drugs reach their targets and achieve their function within our bodies? If a drug molecule or a ligand is a message, an inbox is typically a receptor in the cell membrane. ...

Unexpected Link Between Chromosomal Instability and Epigenetic Alterations

New research finds an unexpected link between chromosomal instability and epigenetic alternations, both of which are hallmarks of cancer -- especially advanced, drug-resistant ...

Biological Clocks of People and Malaria Parasites Tick in Tune

Could the next weapon against malaria come from a better understanding of biological clocks? A new study shows that malaria parasites sync their gene activity with the circadian rhythms of their ...

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Swarming Microrobots Self-Organize Into Diverse Patterns

A research collaboration between Cornell and the Max Planck Institute for Intelligent Systems has found an efficient way to expand the collective behavior of swarming microrobots: Mixing different ...

Previously Unknown Antibiotic Resistance Widespread Among Bacteria

Genes that make bacteria resistant to antibiotics are much more widespread in our environment than was previously realized. A new study shows that bacteria in almost all environments carry resistance ...

Global Response to Antimicrobial Resistance 'Insufficient'

Governments around the world must do more to tackle the growing threat of drug-resistant infections, according to new research. Antimicrobial resistance (AMR) occurs when bacteria, viruses, fungi and ...

New Drug Delays Progression of Glioma, a Deadly Brain Cancer

Scientists have shown that a new targeted therapy drug can extend the amount of time people with a subtype of glioma are on treatment without their cancer worsening. The finding suggests a possible ...

Parkinson's Disease Drug Ropinirole Safely Slowed the Progression of ALS for Over 6 Months in a Clinical Trial

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a fatal motor neuron disease that causes people to gradually lose control of their muscles. There is no cure, and ...

Eye Drops Slow Nearsightedness Progression in Kids

The results of a new clinical trial suggest that the first drug therapy to slow the progression of nearsightedness in kids could be on the horizon. The three-year study found that a daily drop in ...

New Class of Antibiotics to Fight Resistant Bacteria

Health professionals are in urgent need of new antibiotics to tackle resistant bacteria. Researchers have now modified the chemical structure of naturally occurring peptides to develop antimicrobial ...

DNA Damage Repaired by Antioxidant Enzymes

In crisis, the nucleus calls antioxidant enzymes to the rescue. The nucleus being metabolically active is a profound paradigm shift with implications for cancer ...

Lab-Grown Mini Lungs Could Accelerate the Study of Respiratory Diseases

Researchers have collaborated to refine a cell culture technology platform that grows genetically identical lung buds from human embryonic stem ...

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