Apr. 18, 2022 —Researchers have found that heterozygous loss of the methyl-CpG binding protein Zbtb38 downregulated the expression of the transcription factors Nanog and Sox2, as well as genes involved in epiblast ...
Feb. 28, 2022 —A multidisciplinary team has devised a new approach to 3D imaging that captures DNA methylation, a key epigenetic change associated with learning in the brain. The scientists say their ...
Feb. 28, 2022 —In humans and other eukaryotes, two principal epigenetic marks are known. A team has discovered a third, novel epigenetic mark -- one formerly known only in bacteria -- in bdelloid rotifers, small ...
Feb. 10, 2022 —A new study has shown that the effects of pollutants can be transmitted over many generations in water fleas and may persist long enough to influence the evolutionary process. The research adds new ...
Feb. 8, 2022 —Researchers discover a 'switch' specific to transcription factors that induce the genes essential for blood vessel development in postnatal periods. Mouse models further showed that the ...
Jan. 12, 2022 —Hereditary diseases as well as cancers and cardiovascular diseases may be associated with a phenomenon known as genomic imprinting, in which only the maternally or paternally inherited gene is ...
Jan. 11, 2022 —A team has shown that the CLASSY gene family regulates which parts of the genome are turned off in a tissue-specific manner. The work identifies the CLSY genes as major factors underlying epigenetic ...
Jan. 4, 2022 —Researchers generated mice with a specific DNA sequence inverted to determine if orientation affects expression of a gene called H19. Expression can also be impacted if the surrounding DNA is altered ...
July 9, 2021 —A new study provides a potential tool for unraveling the mystery of how experiences can cause inheritable changes to an animal's biology. By mating nematode worms, they produced permanent ...
July 1, 2021 —Hereditary information is passed from parent to offspring in the genetic code, DNA, and epigenetically through chemically induced modifications around the DNA. New research has uncovered a mechanism ...
June 28, 2021 —Researchers noted a significant difference in mice from mothers that were fed a diet rich in canola oil, compared with mothers fed a diet rich in corn oil. A maternal Omega 3-rich diet affected ...
June 21, 2021 —Biologists have discovered 71 new 'imprinted' genes in the mouse genome, a finding that takes them a step closer to unravelling some of the mysteries of epigenetics - an area of science ...
June 7, 2021 —Computer simulations visualize in atomic detail how DNA opens while wrapped around ...
May 20, 2021 —Small chemical 'epigenetic' modifications help plants control their genes. Baby plants erase these modifications to start with a fresh genome every generation. Scientists discovered a gene ...
May 13, 2021 —B cells are the immune cells responsible for creating antibodies, and most produce antibodies in response to a pathogen or a vaccine. A small subset of B cells instead spontaneously make antibodies ...
May 6, 2021 —The cerebellum -- a part of the brain once recognized mainly for its role in coordinating movement -- underwent evolutionary changes that may have contributed to human culture, language and tool use, ...
Apr. 16, 2021 —Scientists have figured out how to modify CRISPR's basic architecture to extend its reach beyond the genome and into what's known as the epigenome -- proteins and small molecules that latch ...
Apr. 15, 2021 —The DNA molecule is not naked in the nucleus. Instead, it is folded in a very organized way by the help of different proteins to establish a unique spatial organization of the genetic information. ...
Apr. 12, 2021 —Histones are tiny proteins that bind to DNA and hold information that can help turn on or off individual genes. Researchers have developed a technique that makes it possible to examine how different ...
Mar. 15, 2021 —All female mammals, including humans, have two X chromosomes. Normal development requires one X chromosome to be inactivated. A balance of protein clusters called cohesins is needed to alter X ...
